Seeley G. Mudd Building

Session 1 Vascular Biology,  Cellular Engineering and Cardiovascular Disease 

Moderator:  Jeffrey LaMack, Department of Biomedical Engineering, Milwaukee School of Engineering

Presentation 1.1  9:00-9:20

Larry McIntire, Wallace Coulter Chair and Professor, Wallace Coulter Department of Biomedical Engineering, Georgia Institute of Technology and Emory University

“ Reversing Flows or Low Mean Wall Stress -- Which is Important?”

Presentation 1.2 9:25-9:45

Peter Tatham, University College, London

“Regulated exocytosis in mast cells”

Presentation 1.3 9:50-10:10

John Tarbell, City University of New York

“The role of apoptosis and mitosis in LDL transport across the endothelium”

Break 10:15-10:35

Session 2 Cell Mechanics and Mechanotransduction

Moderator Charles S. Wallace, Department of Biomedical Engineering, Duke University

Presentation 2.1  10:35-10:55

Robert Nerem, Institute Professor and Director of the Parker H. Petit Institute for Bioengineering and Bioscience, Georgia Institute of Technology

“The Influence of Physical Forces on Cell Behavior”

Presentation 2.2 11:00-11:20

Roger Kamm, Departments of Mechanical Engineering and Biological Engineering, Massachusetts Institute of Technology

“Cytoskeletal rheology and its role in mechanotransduction”

Presentation 2.3  11:25-11:45

Sheldon Weinbaum, City University of New York

“Endothelial glycocalyx and mechanotransduction”

Presentation 2.4 11:50-12:10 Rob Krams, Imperial College London

“Mechano-sensitive signalling pathways also respond to mass transport”

Lunch 12:15-1:15

Session 3  Hemodynamic effects upon the Cardiovascular System In Vivo and In Vitro

Moderator:  Tim McGloughlin, Director, Centre for Applied Biomedical Engineering Research, University of Limerick

Presentation 3.1  1:20-1:40

FJH Gijsen, Biomechanics Laboratory, Erasmus Medical Center, Rotterdam

“Shear stress and atherosclerosis in human coronary arteries”

Presentation 3.2  1:40-2:05

Peter Davies, Robinette Foundation Professor of Cardiovascular Medicine, University of Pennsylvania

“Endothelial fingerprints of athero-susceptibility in an adult swine model”

Presentation 3.3 2:10-2:30

Heather Himburg, Duke University

 “The effect of pulsatile shear stress on vascular endothelial gene expression”

Presentation 3.4 2:35-2:55

Shmuel Einav, State University of New York at Stonybrook

“3-D Biomechanical Analysis of the Vulnerable Plaque's Cap based on Virtual Histology”

Break 3:00-3:15

Session 4.  Hemodynamics and Pathology:  Modeling and Simulation

Moderator: Takami Yamaguchi, Department of Biomedical Engineering, Tohoku University

Presentation 4.1  3:20-3:40

Jay Humphrey, Regents Professor Carolyn S. & Tommie E. Lohman Professor  of Biomedical Engineering, Texas A&M University

 “Modeling Arterial Responses to Altered Hemodynamic Loading”

Presentation 4.2  3:45-4:05

David Steinman, University of Toronto 

“Geometric Risk Factors: From Theory to(wards) Practice”

Presentation 4.3  4:10-4:30

Ajit Yoganathan, Wallace Coulter Department of Biomedical Engineering, Georgia Institute of Technology and Emory University

 “Imaging and Computational Modeling: Their Role in Congenital Heart Surgery”

Presentation 4.4 4:35-4:55

Andrew Hazel, University of Manchester

“Simulating Physiological Fluid-Structure Interaction”

Concluding remarks 5:00- 5:15

Mort Friedman, Department of Biomedical Engineering, Duke University