Stefan Zauscher
Sternberg Family Professor of Mechanical Engineering and Materials Science and Alfred M. Hunt Faculty Scholar and Associate Professor of Biomedical Engineering and Director of Graduate Studies
My research lies at the intersection of surface and colloid science, polymer materials engineering, and biointerface science, with four central areas of focus: 1. Fabrication, manipulation and characterization of stimulus-responsive biomolecular and bio-inspired polymeric nanostructures on surfaces; 2. Nanotechnology of soft-wet materials and hybrid biological/non-biological microdevices; 3. Receptor-ligand interactions relevant to the diagnostics of infectious diseases; 4. Friction of soft-wet materials, specifically the role of glycoproteins on friction in diarthroidal joints. These four broad lines of inquiry deal with fundamental behaviors of soft-wet materials on surfaces and interfaces. The design and fabrication of these interfaces using "smart" polymeric and biomolecular nanostructures, and the characterization of the resulting structures, are critically important for the development of biomolecular sensors and devices and for bioinspired materials. Key approaches and tools I use in my research are: bottom-up organization on the molecular scale, through self-assembly, in-situ polymerization, and manipulation of intermolecular interactions; topdown fabrication, through scanning probe nanolithography; stimulus-responsive polymers; molecular recognition; and new approaches to sensing and manipulation. This research supports Duke's Pratt School of Engineering strategic initiative to expand research in soft-wet Materials Science.
Contact Information:
- Office Location: 3385 CIEMAS
- Office Phone: (919) 660-5360, (919) 660-5310
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Email Address:
Education:
| PhD | University of Wisconsin-Madison | 2000 |
| MS | Oregon State University, Corvallis | 1992 |
Curriculum Vitae
Research Interests:
Nano-mechanical and nano-tribological characterization (elasticity, friction, adhesion) of materials including organic thin films; self-assembled monolayers, polymeric gels, and cellulosics; Fabrication of polymeric nanostructures by scanning probe lithography; Colloidal probe and atomic force microscopy; Single molecule force spectroscopy applied to ligand-receptor binding; Biomolecular nano- and micro sensors
Specialties:
Nanomaterial manufacturing and characterization
Polymer and Protein Engineering
Materials
Nanoscience
Sensing and sensor systems
Manufacturing
Awards, Honors, and Distinctions:
- ICCES Young Investigator Award, International Center for Computational Engineering Sciences, 2008
- NSF Early CAREER Award, National Science Foundation, 2003
- Oak Ridge Associated Universities Faculty Enhancement Award, Oak Ridge Associated Universities, 2001
- Young Investigator Award, American Academy of Nanomedicine, 2005
- Bronze Award for Scientific Achievement, 26th Army Science Conference, U.S. Army Research, 2008
Courses Taught:
- ME 514.01 - THEORTICAL & APPLIED POLY SCI
- ME 555.10 - ADVANCED TOPICS
Representative Publications: (More Publications)
- Tjong, V., Zhang, J., Chilkoti, A., Zauscher, S, Stimulus Responsive Polymers as Intelligent Coatings for Biosensors: Architectures, Response Mechanisms, and Applications (2012).
- Chen, Tao and Jordan, Rainer and Zauscher, Stefan, Extending micro-contact printing for patterning complex polymer brush microstructures, POLYMER, vol 52 no. 12 (2011), pp. 2461-2467 [doi] [abs].
- Yang, Ye and Erb, Randall M. and Wiley, Benjamin J. and Zauscher, Stefan and Yellen, Benjamin B., Imaginary Magnetic Tweezers for Massively Parallel Surface Adhesion Spectroscopy, NANO LETTERS, vol 11 no. 4 (2011), pp. 1681-1684 [doi] [abs].
- Chen, Tao and Jordan, Rainer and Zauscher, Stefan, Polymer brush patterning using self-assembled microsphere monolayers as microcontact printing stamps, SOFT MATTER, vol 7 no. 12 (2011), pp. 5532-5535 [doi] [abs].
- Ferris, R., Hucknall, A., Kwon, B.S., Chilkoti, A., Zauscher, S., Field-Induced Nanolithography for Patterning of Non-Fouling Polymer Brush Surfaces, Small (Accepted, 2011).