Miguel A. Nicolelis

Image of Miguel A. Nicolelis

Professor (primary appt: Neurobiology, Center for Neuroengineering)

Contact Information:
Education:

M.D.University of Sao Paulo (brazil)1984
Ph.D.University of Sao Paulo (brazil)1988

Specialties:

Neural Prosthesis

Courses Taught:
  • BME 494.08 - PROJECTS IN BIOMED ENG
  • BME 493.05 - PROJECTS IN BIOMED ENG

Representative Publications: (More Publications)
    • MA Nicolelis, Brain-machine interfaces to restore motor function and probe neural circuits., Nature reviews. Neuroscience, vol 4 no. 5 (2003), pp. 417-22 [doi].
    • MA Nicolelis, The amazing adventures of robotrat., Trends in cognitive sciences, vol 6 no. 11 (2002), pp. 449-450 [abs].
    • MA Nicolelis, JK Chapin, Controlling robots with the mind., Scientific American, vol 287 no. 4 (2002), pp. 46-53.
    • MA Nicolelis, S Ribeiro, Multielectrode recordings: the next steps., Current opinion in neurobiology, vol 12 no. 5 (2002), pp. 602-6 [abs].
    • DB Katz, MA Nicolelis, SA Simon, Gustatory processing is dynamic and distributed., Current opinion in neurobiology, vol 12 no. 4 (2002), pp. 448-54 [abs].
    • MA Nicolelis, EE Fanselow, Thalamocortical [correction of Thalamcortical] optimization of tactile processing according to behavioral state., Nature neuroscience, vol 5 no. 6 (2002), pp. 517-23 [doi] [abs].
    • MA Nicolelis, Depression at thalamocortical synapses: the key for cortical neuronal adaptation?, Neuron, vol 34 no. 3 (2002), pp. 331-2 [abs].
    • DB Katz, SA Simon, MA Nicolelis, Taste-specific neuronal ensembles in the gustatory cortex of awake rats., The Journal of neuroscience : the official journal of the Society for Neuroscience, vol 22 no. 5 (2002), pp. 1850-7 [abs].
    • MG Shuler, DJ Krupa, MA Nicolelis, Integration of bilateral whisker stimuli in rats: role of the whisker barrel cortices., Cerebral cortex (New York, N.Y. : 1991), vol 12 no. 1 (2002), pp. 86-97 [abs].
    • , Nicolelis MAL, Fanselow EE (2002) Dynamic shifting in thalamocortical processing during different behavior.  Phil Trans R Soc Lond B 357: 1753-1758. (2002).
    • A Das, JG Franca, R Gattass, JH Kaas, MA Nicolelis, C Timo-Iaria, CD Vargas, NM Weinberger, E Volchan, The brain decade in debate: VI. Sensory and motor maps: dynamics and plasticity., Brazilian journal of medical and biological research = Revista brasileira de pesquisas médicas e biológicas / Sociedade Brasileira de Biofísica ... [et al.], vol 34 no. 12 (2001), pp. 1497-508 [abs].
    • EE Fanselow, K Sameshima, LA Baccala, MA Nicolelis, Thalamic bursting in rats during different awake behavioral states., Proceedings of the National Academy of Sciences of the United States of America, vol 98 no. 26 (2001), pp. 15330-5 [doi] [abs].
    • AA Ghazanfar, DJ Krupa, MA Nicolelis, Role of cortical feedback in the receptive field structure and nonlinear response properties of somatosensory thalamic neurons., Experimental brain research. Experimentelle Hirnforschung. Expérimentation cérébrale, vol 141 no. 1 (2001), pp. 88-100 [doi] [abs].
    • JD Kralik, DF Dimitrov, DJ Krupa, DB Katz, D Cohen, MA Nicolelis, Techniques for long-term multisite neuronal ensemble recordings in behaving animals., Methods (San Diego, Calif.), vol 25 no. 2 (2001), pp. 121-50 [doi] [abs].
    • DJ Krupa, MS Matell, AJ Brisben, LM Oliveira, MA Nicolelis, Behavioral properties of the trigeminal somatosensory system in rats performing whisker-dependent tactile discriminations., The Journal of neuroscience : the official journal of the Society for Neuroscience, vol 21 no. 15 (2001), pp. 5752-63 [abs].
    • MG Shuler, DJ Krupa, MA Nicolelis, Bilateral integration of whisker information in the primary somatosensory cortex of rats., The Journal of neuroscience : the official journal of the Society for Neuroscience, vol 21 no. 14 (2001), pp. 5251-61 [abs].
    • DB Katz, SA Simon, MA Nicolelis, Dynamic and multimodal responses of gustatory cortical neurons in awake rats., The Journal of neuroscience : the official journal of the Society for Neuroscience, vol 21 no. 12 (2001), pp. 4478-89 [abs].
    • AA Ghazanfar, MA Nicolelis, Feature article: the structure and function of dynamic cortical and thalamic receptive fields., Cerebral cortex (New York, N.Y. : 1991), vol 11 no. 3 (2001), pp. 183-93 [abs].
    • DJ Krupa, AJ Brisben, MA Nicolelis, A multi-channel whisker stimulator for producing spatiotemporally complex tactile stimuli., Journal of neuroscience methods, vol 104 no. 2 (2001), pp. 199-208 [abs].
    • , Katz DB, Simon SA, Nicolelis MAL (2001) Electrophysiological studies of gustation in awake rats. In: Methods in Chemosensory Research (Methods and New Frontiers in Neuroscience Series, M.A.L. Nicolelis and S.A. Simon, eds.) CRC Press, pp. 339-357. (2001).
    • , Nicolelis MAL. Actions from thoughts.  Nature.  2001 Jan 18;409 Suppl:403-407. (2001).
    • MA Nicolelis, M Shuler, Thalamocortical and corticocortical interactions in the somatosensory system., Progress in brain research, vol 130 (2001), pp. 90-110.
    • , Faneslow EE, Reid AP, Nicolelis MAL (2000)  Reduction of pentylenetetrazole-induced seizure activity in awake rats by seizure-triggered trigeminal nerve stimulation. J Neurosci 20: 8160-8168. (2000).
    • , Ghazanfar AA, Nicolelis MAL (2000) The space-time continuum in mammalian sensory pathways. In: Time and the Brain (R. Miller, ed.) Harwood Academic Publishers, Sidney, Australia, pp. 97-130. (2000).
    • , Ghazanfar AA, Stambaugh CR, Nicolelis MAL (2000) Encoding of tactile stimulus location by somatosensory thalamocortical ensembles. J Neurosci 20: 3761-3775. (2000).
    • , Katz DB, Nicolelis MAL, Simon SA (2000) There is more to taste than meets the tongue. Am J Physiol 278: G6-G9. (2000).
    • , Krupa DJ, Nicolelis MAL (2000) Network level properties of short-term plasticity in the somatosensory system. Prog Brain Res 128:161-172. (2000).
    • , Laubach M, Wessberg J, Nicolelis MAL (2000) Cortical ensemble activity increasingly predicts behavioral outcomes during learning of a motor task. Nature 405: 567-571. (2000).
    • , Wessberg J,  Stambaugh CR,  Kralik JD,  Beck PD,  Laubach M, Chapin JK,  Kim J,  Biggs SJ, Srinivasan MA, Nicolelis MAL (2000) Real-time prediction of hand trajectory by ensembles of cortical neurons in primates. Nature 408: 361-365. (2000).
    • , Chapin JK, Nicolelis MAL (1999) Principal component analysis of neuronal ensemble activity reveals multidimensional sensory representations. J Neurosci Meth 94: 121-140. (1999).
    • , Chapin JK,  Markowitz RS,  Moxon KA, Nicolelis MAL (1999) Real-time control of a robot arm using simultaneously recorded neurons in the motor cortex. Nature Neurosci 2: 664-670. (1999).
    • , Fanselow E, Nicolelis MAL (1999) Behavioral modulation of tactile responses in the rat somatosensory system. J Neurosci 19: 7603-7616. (1999).
    • , Ghazanfar AA, Nicolelis MAL (1999) Spatiotemporal properties of layer V neurons in the rat primary somatosensory cortex. Cerebral Cortex 9: 348-361. (1999).
    • , Katz DB, Simon SA, Nicolelis MAL  (1999) Simultaneous reorganization in thalamcortical ensembles evolves over several hours after perioral capsaicin injections. J Neurophysiol 82: 963-977. (1999).
    • , Krupa DJ, Ghazanfar AA, Nicolelis MAL (1999) Immediate thalamic sensory plasticity depends on corticothalamic feedback. Proc Natl Acad Sci USA 96: 8200-8205. (1999).
    • , Laubach M, Shuler M, Nicolelis MAL (1999) Independent component analyses for quantifying neuronal ensemble interactions. J Neurosci Meth 94: 141-154. (1999).
    • , Nicolelis MAL, Ghazanfar AA, Oliveira LMO, Chapin JK, Nelson R, Kaas JH (1998) Simultaneous encoding of tactile information by three primate cortical areas. Nature Neurosci 1: 621-630. (1998).
    • , Faggin B, Ngyuen KT, Nicolelis MAL (1997)  Immediate and simultaneous plastic reorganization at multiple levels of the somatosensory system.  Proc Natl Acad Soc USA 94:9428-9433. (1997).
    • , Ghazanfar AA,  Nicolelis MAL (1997)  Non-linear processing of tactile information in the thalamocortical loop.  J Neurophysiol 78:506-510. (1997).
    • , Lin CS, Nicolelis MAL, Chapin JK (1997) Topography and laminar organization of the incertocortical pathway in rats.  Neuroscience 81: 641-651. (1997).
    • , Nicolelis MAL (1997)  Dynamic and distributed somatosensory organization as the substrate for cortical and subcortical plasticity. Seminars in Neurosciences 9:24-33. (1997).
    • , Nicolelis MAL, Fanselow E, Ghazanfar AA (1997) Hebb's dream:  The resurgence of cell assemblies.  Neuron 19(2):219-221. (1997).
    • , Nicolelis MAL, Ghazanfar AA, Faggin B, Votaw S, Oliveira LMO (1997) Reconstructing the engram:  simultaneous, multiple site, many single neuron recordings. Neuron 18:529-537 (1997).
    • , Nicolelis MAL, Lin RCS, Chapin JK (1997)  Neonatal whisker removal reduces the discrimination of tactile stimuli by thalamic ensembles in adult rats.  J Neurophysiol 78: 1691-1706. (1997).
    • , Chapin JK, Nicolelis MAL (1996) Neural network mechanisms of oscillatory brain states: characterization using simultaneous multi-single neuron recordings., In: Continuous waveform analysis, R.M. Basheiss and D.J. Vicent (eds). Electroenceph Clin Neurophysiol, suppl 45, pp 113-122. (1996).
    • , Lin RCS, Nicolelis MAL, Zhou HL, Chapin JK (1996) Calbindin-containing, non-specific thalamocortical projecting neurons in the rat. Brain Research 711: 50-55. (1996).
    • , Nicolelis MAL (1996)  Beyond maps: A dynamic view of the somatosensory system. Braz J Med Biol Res 29: 401-412. (1996).
    • , Nicolelis MAL, Oliveira LMO, Lin RCS, Chapin JK (1996) Active tactile exploration influences the functional maturation of the somatosensory system. J Neurophysiol 17: 2192-2196. (1996).
    • , Chapin JK, Nicolelis MAL (1995)  Beyond single unit recording: Characterizing neural information in networks of simultaneously recorded neurons.  In: Scale in Conscious Experience, eds. J. King and K.H. Pribram.  Lawrence Erlbaum Assoc., New Jersey, pp. 133-153. (1995).
    • , Nicolelis MAL, Baccala LA, Lin RCS, Chapin JK  (1995) Sensorimotor encoding by synchronous neural ensemble activity at multiple levels of the somatosensory system. Science 268: 1353-1358. (1995).
    • , Nicolelis MAL, Chapin JK, Lin RCS (1995)  Development of the direct projections from the zona incerta to the primary somatosensory cortex in rats.  Neurosci 65: 609-631. (1995).
    • , Bennett-Clarke CA, Nicolelis MAL, Jacquin MF (1994) Proceedings of a satellite symposium of the 1993 Society for Neuroscience Meeting. Somat Mot Res 11: 197-204. (1994).
    • , Nicolelis MAL, Chapin JK (1994) Spatiotemporal structure of somatosensory responses of many-neuron ensembles in the rat ventral posterior medial nucleus of the thalamus. J Neurosci 14: 3511-3532. (1994).
    • , Nicolelis MAL, Lin RCS, Woodward DJ, Chapin JK (1993) Dynamic and distributed properties of many-neuron ensembles in the ventral posterior medial (VPM) thalamus of awake rats. Proc Natl Acad Sci USA 90: 2212-2216. (1993).
    • , Nicolelis MAL, Lin RCS, Woodward DJ, Chapin JK (1993) Peripheral block of ascending cutaneous information induces immediate spatiotemporal changes in thalamic networks. Nature 361: 533-536. (1993).
    • , Lin CS,  Nicolelis MAL, Schneider JS, Chapin JK (1990) A major direct GABAergic pathway from zona incerta to neocortex. Science 248: 1553-1556. (1990).