Jingdong Tian
Assistant Professor
Dr. Tian's research interests include synthetic biology, advanced biomolecular and biosystems engineering and genome science.
The lab currently has two focus areas:
1) Developing enabling technologies for large scale synthetic biology and functional genomics.
2) Applying high-throughput gene and genome synthesis and optimization technologies for understanding design principles of natural and synthetic biological systems.
Ongoing projects include:
Developing high-throughput, high-fidelity and low-cost gene and genome synthesis platform;
Developing efficient and reliable gene design and protein expression optimization technology;
Developing efficient protein design and directed evolution strategies;
Metabolic engineering;
BioMEMS, instrumentation, and software development.
Contact Information:
- Office Location: 1383 Fciemas
- Office Phone: (919) 684-3494
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Email Address:
Education:
| PhD | Stony Brook University | |
| Postdoctoral | Harvard Medical School |
Awards, Honors, and Distinctions:
- Hartwell Individual Biomedical Research Award
- Beckman Young Investigator Award
- Life Sciences Research Foundation Postdoctoral Fellow
- Sigma Xi Excellence in Graduate Research Award
Courses Taught:
- BME 258L - GENOME SCIENCE TECHNOLOGY LAB
- BME 83L - INTRO TO BIOMATERIALS
Representative Publications: (More Publications)
- Quan J, Saaem I, Tang N, Ma S, Negre N, Gong H, White KP & Tian J., Parallel on-chip gene synthesis and application to optimization of protein expression, Nature Biotechnology, vol 29 (2011), pp. 449-452 [html].
- Quan J & Tian J, Circular polymerase extension cloning for high-throughput cloning of complex and combinatorial DNA libraries, Nature Protocols, vol 6 (2011), pp. 242-251 [html].
- Ma S, Saaem I, and Tian J, Error correction in gene synthesis technology, Trends in Biotechnology (2011) [S0167-7799(11)00179-X] (Epub ahead of Print.) .
- Saaem I, Ma S, Quan J, and Tian J, Error correction of microchip synthesized genes using Surveyor nuclease, Nucleic Acids Research (2011) [full] (Epub ahead of Print.) .
- Tian J, Gong H, Sheng N, Zhou X, Gulari E, Gao X, and Church GM, Accurate multiplex gene synthesis from programmable DNA microchips, Nature, vol 432 (2004), pp. 1050-1054 [nature03151].