Charles Gersbach

Image of Charles Gersbach

Assistant Professor of Biomedical Engineering

Appointments and Affiliations
  • Assistant Professor of Biomedical Engineering
  • Assistant Professor of Orthopaedic Surgery
Contact Information:
  • Office Location: 2353C Ciemas, Durham, NC 27708
  • Office Phone: (919) 613-2147
  • Email Address: charles.gersbach@duke.edu
  • Web Page:
Education:

  • Ph.D. Georgia Institute of Technology, 2006
  • B.S. Georgia Institute of Technology, 2001

Research Interests:

Dr. Gersbach’s research interests are in gene therapy, biomolecular and cellular engineering, regenerative medicine, and synthetic biology.

Specialties:

Drug Delivery
Genomics
Tissue Repair, Tissue Engineering
Polymer and Protein Engineering
Biological Materials

Awards, Honors, and Distinctions:

  • Capers and Marion McDonald Award for Excellence in Teaching and Research, 2013
  • NSF Faculty Early Career Development (CAREER) Award, 2012
  • Basil O'Connor Starter Scholar Research Award, March of Dimes, 2011
  • NIH Director's New Innovator Award, 2011
  • Ralph E. Powe Junior Faculty Enhancement Award, Oak Ridge Associated Universities, 2011
  • Scientist Development Grant, American Heart Association, 2010
  • Hartwell Individual Biomedical Research Award, 2009
  • National Cancer Institute Postdoctoral Fellowship, 2007-2009
  • F.L. Suddath Memorial Award, 2005
  • National Institutes of Health National Research Service Award, 2002-2004
  • Georgia Institute of Technology President’s Scholarship, 1998

Courses Taught:
  • BME 260L: Modeling Cellular and Molecular Systems
  • BME 394: Projects in Biomedical Engineering (GE)
  • BME 493: Projects in Biomedical Engineering (GE)
  • BME 494: Projects in Biomedical Engineering (GE)
  • BME 562: Biology by Design (GE, MC)
  • BME 590: Advanced Topics in Biomedical Engineering
  • BME 590: Special Topics in Biomedical Engineering
  • BME 711S: Biological Engineering Seminar Series (CBIMMS and CBTE)
  • BME 712S: Biological Engineering Seminar Series (CBIMMS and CBTE)
  • BME 899: Special Readings in Biomedical Engineering
  • GENOME 293: Research Independent Study Genome Sciences
  • GENOME 294: Research Independent Study Genome Sciences
  • ME 717S: Biological Engineering Seminar Series (CBIMMS and CBTE)
  • ME 718S: Biological Engineering Seminar Series (CBIMMS and CBTE)

Representative Publications: (More Publications)
    • Gersbach, CA; Gaj, T; Barbas, CF, Comparing Genome Editing Technologies, Genetic Engineering and Biotechnology News, vol 34 no. 5 (2014), pp. 1, 32-34 [10.1089/gen.34.05.02] [abs].
    • Perez-Pinera, P; Kocak, DD; Vockley, CM; Adler, AF; Kabadi, AM; Polstein, LR; Thakore, PI; Glass, KA; Ousterout, DG; Leong, KW; Guilak, F; Crawford, GE; Reddy, TE; Gersbach, CA, RNA-guided gene activation by CRISPR-Cas9-based transcription factors., Nature Methods, vol 10 no. 10 (2013), pp. 973-976 [10.1038/nmeth.2600] [abs].
    • Ousterout, DG; Perez-Pinera, P; Thakore, PI; Kabadi, AM; Brown, MT; Qin, X; Fedrigo, O; Mouly, V; Tremblay, JP; Gersbach, CA, Reading frame correction by targeted genome editing restores dystrophin expression in cells from Duchenne muscular dystrophy patients., Molecular Therapy, vol 21 no. 9 (2013), pp. 1718-1726 [10.1038/mt.2013.111] [abs].
    • Gaj, T; Gersbach, CA; Barbas, CF, ZFN, TALEN, and CRISPR/Cas-based methods for genome engineering., Trends in Biotechnology, vol 31 no. 7 (2013), pp. 397-405 [10.1016/j.tibtech.2013.04.004] [abs].
    • Dumbauld, DW; Lee, TT; Singh, A; Scrimgeour, J; Gersbach, CA; Zamir, EA; Fu, J; Chen, CS; Curtis, JE; Craig, SW; García, AJ, How vinculin regulates force transmission., Proceedings of the National Academy of Sciences of USA, vol 110 no. 24 (2013), pp. 9788-9793 [10.1073/pnas.1216209110] [abs].